Calcified Granulomatous Pneumocystis Jirovecii Pneumonia in a Toddler with Severe Combined Immunodeficiency—A Case Report

نویسندگان

چکیده

Pneumocysis jirovecii pneumonia (PJP) is a type of originating from the fungus Pneumocystis jiroveci and major cause serious in immunocompromised conditions. PJP typically appears as bilateral diffuse pulmonary infiltrates. Granulomatous an uncommon form pneumocystis infection, occurring only 3% to 5% patients. Calcification exceptional. We present 9-month-old boy affected by Severe Combined Immunodeficiency (SCID) that has been diagnosed at age 7 months following lung infection. He underwent routine total-body magnetic resonance imaging (MRI) prior allogeneic hematopoietic stem cell transplantation (HSCT). The MRI showed significant alterations parenchyma; hence, computer tomography was performed showing presence 11 calcified granulomatous nodules. report unique case toddler SCID. Awareness this rare yet possible presentation patients with SCID important given potential clinical implications when managing patient undergoing HSCT it further enhances importance advanced radiologic HSCT.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Survival after Pneumocystis jirovecii pneumonia requiring ventilation: A case report

Pneumocystis pneumonia (PCP) in patients with the human immunodeficiency virus (HIV) is associated with a high mortality rate, which increases substantially with the need for mechanical ventilation. Local experience of patients with PCP admitted to the intensive care unit has revealed mortality rates close to 100%. We present a case of a 39-year-old HIV-infected man diagnosed with PCP who was s...

متن کامل

A case of severe combined immunodeficiency presenting with CMV pneumonia

A five month-old girl was admitted in Ali Asghar Children’s Hospital with a history of three months of fever, cough and dyspnea that her symptoms have exacerbated since two weeks before admission. She was the first child of the family born to consanguineous parents. She was clinically healthy in the past and had gained weight normally and undergone vaccination program with no complication unti...

متن کامل

Pneumocystis jirovecii Pneumonia

Pneumocystis jirovecii (formerly Pneumocystis carinii sp. f. hominis) is an unusual fungus exhibiting pulmonary tropism and a highly defined host specificity. It is generally regarded as an opportunistic microorganism causing severe and often fatal pneumonia in AIDS patients. However, with the currently rising number of patients receiving immunosuppressive therapies for malignancies, allogeneic...

متن کامل

Severe combined immunodeficiency presented with septic arthritis: A case report

Severe combined immunodeficiency is a rare, fatal syndrome of diverse genetic cause in which there is combined absence of T-lymphocyte and B-lymphocyte function (and in many cases also natural killer, or NK lymphocyte function). These defects lead to extreme susceptibility to serious infections. Without intervention, the T and B-cell dysfunction usually results in severe infection and death in ...

متن کامل

Pneumocystis jirovecii Pneumonia in Pediatric Inflammatory Bowel Disease: A Case Report and Literature Review

Immunosuppressive therapy is a known risk factor for opportunistic infections. We report the first case of severe Pneumocystis jirovecii infection requiring intensive care in a pediatric patient with inflammatory bowel disease (IBD). The literature was reviewed and there were 92 reported cases of Pneumocystis pneumonia (PCP) in patients with IBD. Most sources were case reports and there was lik...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Transplantology

سال: 2022

ISSN: ['2673-3943']

DOI: https://doi.org/10.3390/transplantology3040029